We test for all of the following Inherited Disease. Results of these tests are noted in each dogs profile. These tests identify dogs that are carriers for inherited diseases to enhance breed improvement programs. Effected can be successfully bred to non-carriers of any inherited diseases. Offspring may be carriers but will not develop the disease. It is important to us to do all genetic clearances.
Cystinuria is an inherited autosomal recessive disorder and is characterized by the formation of cystine stones in the kidney, ureter, and bladder.
Exercise Induced Collapse Dogs clinically affected by (EIC) will often begin to exhibit leg weakness followed by a complete collapse after just 5 to 15 minutes of strenuous activity.
Hyperuricosuria, or elevated uric acid level in the urine, is inherited as an autosomal recessive disorder and is characterized by the formation of bladder stones and occasional kidney stones.
Hereditary Nasal Parakeratosis (HNPK) is an inherited autosomal recessive disorder. Affected dogs begin showing clinical signs around six to twelve months of age. They develop dry, rough crusts on the tip of the nose. In extreme cases, the nose will crack causing severe discomfort.
Long-haired coat length is inherited as an autosomal recessive trait. Therefore, dogs that are carriers of the long-hair mutation usually appear to be normal (short hair) but will likely pass on the long-hair allele 50% of the time.
D Locus-associated with the dilution or lightening effect of solid colors, with D being the dominant allele, the dd genotype results in the diluted effect (like grey, blue, silver, lilac, champagne). D-locus is carried in 'Silver, Champagne & Charcoal' dogs being called Labradors.
Congenital Myasthenic Syndrome: (CMS) is a neuromuscular disorder in Labrador Retrievers characterized by generalized muscle weakness and fatigue, often induced by exercise.
Cone Degeneration: is an inherited eye disease affecting dogs. Affected dogs develop day blindness (blindness in bright light) and Photophobia (light sensitivity) between 8 to 12 weeks after birth due to degeneration of cells in the eye called cone photoreceptors which are responsible for vision in bright light
Degenerative Myelopathy: (DM) is a disease that affects the spinal cord in dogs, causing progressive muscle weakness and loss of coordination. It acts similarly to Lou Gehrig's disease, or ALS (amyotrophic lateral sclerosis), in humans.
Elliptocytosis: is a hereditary disorder of the red blood cells (RBCs). In this condition, the RBCs assume an elliptical shape, rather than the typical round shape. Blood is comprised of red blood cells, platelets, and various white blood cells. Elliptocytosis is a hereditary disorder of the red blood cells (RBCs)
Ichthyosis: Ichthyosis is a very rare skin condition in dogs that is the result of a genetic mutation. The mutation prevents the outer layer of skin from developing properly.
Intervertebral Disc Disease Risk Factor (CDDY with IVDD): Intervertebral disc disease associated with the CFA12 FGF4 mutation is inherited in an Autosomal Dominant manner meaning that a dog only needs to inherit one copy of the mutated gene to be at an increased risk of developing the disease.
Myotubular Myopathy 1: is an inherited muscle disease known to affect Labrador Retrievers. Affected puppies are typically normal at birth, but between 7 and 19 weeks of age they present with muscle weakness especially in the hind limbs, decreased muscle mass, a hoarse bark and difficulty eating.
Narcolepsy: is a disorder of the nervous system, affecting primarily young dogs and cats. A narcoleptic episode involves sudden collapse and loss of movement. The pet literally falls asleep, often while physically active, then wakes up abruptly and proceeds as if nothing happened
Progressive Retinal Atrophy, Cone-Rod DProgressive Retinal Atrophy 4: Progressive retinal Atrophy, cone-Rod dystrophy 4 (PRA-crd4) is an inherited eye disease affecting dogs. PRA-crd4 occurs as a result of degeneration of both rod and cone type Photoreceptor Cells of the Retina, which are important for vision in dim and bright light, respectively.
Progressive Retinal Atrophy, Progressive Rod-Cone Degeneration: (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds. PRCD affects the photoreceptor cells in the eye involved in both night and day vision.
Pyruvate Kinase Deficiency: (PKDef) is an inherited hemolytic anemia caused by a defect in the enzyme pyruvate kinase. Loss of function of this enzyme results in premature death of red blood cells. Affected dogs do not have sufficient quantities of red blood cells to adequately supply the body with oxygen.
Retinal Dysplasia/Oculoskeletal Dysplasia 1: (RD) is abnormal development of the retina.
Skeletal Dysplasia 2: (SD2) is an inherited musculoskeletal disorder that causes a form of mild disproportionate dwarfism in affected dogs – their body length and width are normal, but their legs are shorter than normal.
Stargardt Disease: is a degenerative eye disorder resulting from the progressive loss of the photoreceptor cells that are responsible for sensing light. Affected dogs show a decline in vision with age but appear to retain some vision throughout their life.
Copper Toxicosis (CT): (CT) is an inherited autosomal recessive disorder in which a dog's system accumulates excess copper instead of excreting it naturally. CT affects several dog breeds and can result in severe damage to the liver and—eventually—liver disease, failure, and possibly death.